Irritable bowel syndrome (IBS) is a very common disorder characterized by cramping, abdominal pain, bloating, constipation, and/or diarrhea. IBS causes a great deal of discomfort and distress, but it does not permanently harm the intestines and does not lead to a more serious disease, such as cancer. Most people can control their symptoms with a combination of diet, stress management, and prescribed medications. For some people, however, IBS can be disabling. They may be unable to work, attend social events, or even travel short distances.